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BMCBI
2010
130views more  BMCBI 2010»
15 years 19 days ago
MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligat
Background: Multiplex Ligation-Dependent Probe Amplification (MLPA) is an application that can be used for the detection of multiple chromosomal aberrations in a single experiment...
Ronald van Eijk, Paul H. C. Eilers, Remco Natt&eac...
BMCBI
2010
162views more  BMCBI 2010»
15 years 19 days ago
SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...
Hsueh-Wei Chang, Yu-Huei Cheng, Li-Yeh Chuang, Che...
BMCBI
2010
167views more  BMCBI 2010»
15 years 19 days ago
BisoGenet: a new tool for gene network building, visualization and analysis
Background: The increasing availability and diversity of omics data in the post-genomic era offers new perspectives in most areas of biomedical research. Graph-based biological ne...
Alexander Martin, Maria Elena Ochagavia, Laya C. R...
BMCBI
2010
179views more  BMCBI 2010»
15 years 19 days ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
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BMCBI
2010
102views more  BMCBI 2010»
15 years 19 days ago
SAMPLEX: Automatic mapping of perturbed and unperturbed regions of proteins and complexes
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
Mickaël Krzeminski, Karine Loth, Rolf Boelens...
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