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105
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BMCBI
2004
92views more  BMCBI 2004»
15 years 9 days ago
BioBuilder as a database development and functional annotation platform for proteins
Background: The explosion in biological information creates the need for databases that are easy to develop, easy to maintain and can be easily manipulated by annotators who are m...
J. Daniel Navarro, Naveen Talreja, Suraj Peri, B. ...
BMCBI
2004
177views more  BMCBI 2004»
15 years 9 days ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
135
Voted
BMCBI
2004
110views more  BMCBI 2004»
15 years 9 days ago
Tools for loading MEDLINE into a local relational database
Background: Researchers who use MEDLINE for text mining, information extraction, or natural language processing may benefit from having a copy of MEDLINE that they can manage loca...
Diane E. Oliver, Gaurav Bhalotia, Ariel S. Schwart...
BMCBI
2004
136views more  BMCBI 2004»
15 years 9 days ago
A SNP-centric database for the investigation of the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are an increasingly important tool for genetic and biomedical research. Although current genomic databases contain information o...
Alberto Riva, Isaac S. Kohane
109
Voted
BMCBI
2004
228views more  BMCBI 2004»
15 years 9 days ago
An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
Romesh Stanislaus, Liu Hong Jiang, Martha Swartz, ...
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