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BIOINFORMATICS
2010
127views more  BIOINFORMATICS 2010»
14 years 10 months ago
Analyzing taxonomic classification using extensible Markov models
Motivation: As next generation sequencing is rapidly adding new genomes, their correct placement in the taxonomy needs verification. However, the current methods for confirming cl...
Rao M. Kotamarti, Michael Hahsler, Douglas Raiford...
BMCBI
2010
87views more  BMCBI 2010»
14 years 10 months ago
poolMC: Smart pooling of mRNA samples in microarray experiments
Background: Typically, pooling of mRNA samples in microarray experiments implies mixing mRNA from several biological-replicate samples before hybridization onto a microarray chip....
Raghunandan M. Kainkaryam, Angela Bruex, Anna C. G...
BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2010
156views more  BMCBI 2010»
14 years 10 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
BMCBI
2010
175views more  BMCBI 2010»
14 years 10 months ago
Saliva Ontology: An ontology-based framework for a Salivaomics Knowledge Base
Background: The Salivaomics Knowledge Base (SKB) is designed to serve as a computational infrastructure that can permit global exploration and utilization of data and information ...
Jiye Ai, Barry Smith, Wong T. David
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