Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Scientists face an ever-increasing challenge in investigating biological systems with high throughput experimental methods such as mass spectrometry and gene arrays because of the...
Eric G. Stephan, Kyle R. Klicker, Mudita Singhal, ...
Background: Genetic regulatory networks (GRN) can be described by differential equations with SUM logic which has been found in many natural systems. Identification of the network...