69 search results - page 8 / 14 » Integrating sequence and structural biology with DAS |
115
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DEXAW
2006
IEEE
15 years 1 months ago
2006
IEEE
The availability of a direct pathway from a primary sequence (denovo or DNA derived) to macromolecular structure to biological function using computer-based tools is the ultimate ...
BMCBI
2010
14 years 12 months ago
2010
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
BICOB
2010
Springer
14 years 9 months ago
2010
Springer
Fold recognition is a key problem in computational biology that involves classifying protein sharing structural similarities into classes commonly known as "folds". Rece...
101
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BMCBI
2010
14 years 12 months ago
2010
Background: With the rapidly falling cost and availability of high throughput sequencing and microarray technologies, the bottleneck for effectively using genomic analysis in the ...
98
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BMCBI
2007
14 years 11 months ago
2007
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...