A legacy system is an operational, large-scale software system that is maintained beyond its first generation of programmers. It typically represents a massive economic investmen...
Kostas Kontogiannis, Renato de Mori, Morris Bernst...
Background: Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays...
Ravi Vijaya Satya, Kamal Kumar, Nela Zavaljevski, ...
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical proce...
Andreas Keller, Christina Backes, Maher Al-Awadhi,...
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Model-Driven Engineering (MDE) has been advocated as an effective way to deal with today's software complexity. MDE can be seen as an integrative approach combining existing ...