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» Integrative Analysis of Protein Interaction Data
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BMCBI
2010
126views more  BMCBI 2010»
14 years 7 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
NAR
2007
155views more  NAR 2007»
14 years 9 months ago
Influenza Virus Database (IVDB): an integrated information resource and analysis platform for influenza virus research
Frequent outbreaks of highly pathogenic avian influenza and the increasing data available for comparative analysis require a central database specialized in influenza viruses (IVs...
Suhua Chang, Jiajie Zhang, Xiaoyun Liao, Xinxing Z...
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
AIMSA
2004
Springer
15 years 3 months ago
PubMiner: Machine Learning-Based Text Mining System for Biomedical Information Mining
PubMiner, an intelligent machine learning based text mining system for mining biological information from the literature is introduced. PubMiner utilize natural language processing...
Jae-Hong Eom, Byoung-Tak Zhang
BMCBI
2004
93views more  BMCBI 2004»
14 years 9 months ago
Predicting binding sites of hydrolase-inhibitor complexes by combining several methods
Background: Protein-protein interactions play a critical role in protein function. Completion of many genomes is being followed rapidly by major efforts to identify interacting pr...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...