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» Integrative Analysis of Protein Interaction Data
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BMCBI
2005
118views more  BMCBI 2005»
14 years 9 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz
BMCBI
2007
142views more  BMCBI 2007»
14 years 9 months ago
LinkHub: a Semantic Web system that facilitates cross-database queries and information retrieval in proteomics
nd: A key abstraction in representing proteomics knowledge is the notion of unique identifiers for individual entities (e.g. proteins) and the massive graph of relationships among...
Andrew K. Smith, Kei-Hoi Cheung, Kevin Y. Yip, Mar...
RECOMB
2008
Springer
15 years 10 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
WOB
2004
14 years 11 months ago
An Integrated Model for Cellular Analysis
ABSTRACT. We present the MOlecular NETwork (MONET) ontology as a model to integrate data from different networks that govern cell function. To achieve this, different existing onto...
Eduardo Battistella, José Souza, Clá...
VIS
2009
IEEE
238views Visualization» more  VIS 2009»
15 years 11 months ago
An Interactive Visualization Tool for Multi-channel Confocal Microscopy Data in Neurobiology Research
Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure of the nervous system. Confocal image data are often multi-channel, with each channe...
Yong Wan, Hideo Otsuna, Chi-Bin Chien, Charles ...