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» Integrative missing value estimation for microarray data
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SAC
2003
ACM
15 years 2 months ago
A Markov Random Field Model of Microarray Gridding
DNA microarray hybridisation is a popular high throughput technique in academic as well as industrial functional genomics research. In this paper we present a new approach to auto...
Mathias Katzer, Franz Kummert, Gerhard Sagerer
123
Voted
BIOCOMP
2006
14 years 11 months ago
Dynamic Bayesian Network (DBN) with Structure Expectation Maximization (SEM) for Modeling of Gene Network from Time Series Gene
Exploring gene regulatory network is a key topic in molecular biology. In this paper, we present a new dynamic Bayesian network (DBN) framework embedded with structural expectatio...
Yu Zhang, Zhidong Deng, Hongshan Jiang, Peifa Jia
69
Voted
BMCBI
2005
126views more  BMCBI 2005»
14 years 9 months ago
An algorithm for automatic evaluation of the spot quality in two-color DNA microarray experiments
Background: Although DNA microarray technologies are very powerful for the simultaneous quantitative characterization of thousands of genes, the quality of the obtained experiment...
Eugene Novikov, Emmanuel Barillot
93
Voted
AIME
2007
Springer
15 years 3 months ago
Interpreting Gene Expression Data by Searching for Enriched Gene Sets
This paper presents a novel method integrating gene-gene interaction information and Gene Ontology for the construction of new gene sets that are potentially enriched. Enrichment o...
Igor Trajkovski, Nada Lavrac
100
Voted
BMCBI
2005
135views more  BMCBI 2005»
14 years 9 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...