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BMCBI
2011
15 years 1 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
BMCBI
2011
15 years 1 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
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BMCBI
2011
15 years 1 months ago
Meta-analysis of gene expression microarrays with missing replicates
Background: Many different microarray experiments are publicly available today. It is natural to ask whether different experiments for the same phenotypic conditions can be combin...
Fan Shi, Gad Abraham, Christopher Leckie, Izhak Ha...
BMCBI
2011
15 years 1 months ago
Empirical Bayesian models for analysing molecular serotyping microarrays
Background: Microarrays offer great potential as a platform for molecular diagnostics, testing clinical samples for the presence of numerous biomarkers in highly multiplexed assay...
Richard Newton, Jason Hinds, Lorenz Wernisch
MMAS
2011
Springer
15 years 1 months ago
Scalable Bayesian Reduced-Order Models for Simulating High-Dimensional Multiscale Dynamical Systems
While existing mathematical descriptions can accurately account for phenomena at microscopic scales (e.g. molecular dynamics), these are often high-dimensional, stochastic and thei...
Phaedon-Stelios Koutsourelakis, Elias Bilionis
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