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117
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BMCBI
2010
105views more  BMCBI 2010»
15 years 26 days ago
Comparison of PGH2 binding site in prostaglandin synthases
Background: Prostaglandin H2 (PGH2) is a common precursor for the synthesis of five different Prostanoids via specific Prostanoid Synthases. The binding of this substrate with the...
Padmapriya Paragi-Vedanthi, Mukesh Doble
109
Voted
BMCBI
2010
227views more  BMCBI 2010»
15 years 26 days ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman
BMCBI
2010
104views more  BMCBI 2010»
15 years 26 days ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong
100
Voted
BMCBI
2007
121views more  BMCBI 2007»
15 years 26 days ago
Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines
Background: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epito...
Huynh-Hoa Bui, John Sidney, Wei Li, Nicholas Fusse...
BMCBI
2010
102views more  BMCBI 2010»
15 years 26 days ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
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