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BMCBI
2007
121views more  BMCBI 2007»
15 years 4 months ago
Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines
Background: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epito...
Huynh-Hoa Bui, John Sidney, Wei Li, Nicholas Fusse...
BMCBI
2010
102views more  BMCBI 2010»
15 years 4 months ago
Quantized correlation coefficient for measuring reproducibility of ChIP-chip data
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Shouyong Peng, Mitzi I. Kuroda, Peter J. Park
BMCBI
2010
117views more  BMCBI 2010»
15 years 4 months ago
MetAssimulo: Simulation of Realistic NMR Metabolic Profiles
Background: Probing the complex fusion of genetic and environmental interactions, metabolic profiling (or metabolomics/metabonomics), the study of small molecules involved in meta...
Harriet J. Muncey, Rebecca Jones, Maria De Iorio, ...
BMCBI
2010
120views more  BMCBI 2010»
15 years 4 months ago
Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
Kang Ning, Hoong Kee Ng, Sriganesh Srihari, Hon Wa...
BMCBI
2007
137views more  BMCBI 2007»
15 years 4 months ago
GEVALT: An integrated software tool for genotype analysis
Background: Genotype information generated by individual and international efforts carries the promise of revolutionizing disease studies and the association of phenotypes with al...
Ofir Davidovich, Gad Kimmel, Ron Shamir
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