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BMCBI
2007
110views more  BMCBI 2007»
15 years 4 months ago
Analysis of feedback loops and robustness in network evolution based on Boolean models
Background: Many biological networks such as protein-protein interaction networks, signaling networks, and metabolic networks have topological characteristics of a scale-free degr...
Yung-Keun Kwon, Kwang-Hyun Cho
BMCBI
2008
152views more  BMCBI 2008»
15 years 4 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
BMCBI
2010
112views more  BMCBI 2010»
15 years 4 months ago
The MetabolomeExpress Project: enabling web-based processing, analysis and transparent dissemination of GC/MS metabolomics datas
Background: Standardization of analytical approaches and reporting methods via community-wide collaboration can work synergistically with web-tool development to result in rapid c...
Adam J. Carroll, Murray R. Badger, A. Harvey Milla...
BMCBI
2008
133views more  BMCBI 2008»
15 years 4 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
BMCBI
2007
111views more  BMCBI 2007»
15 years 4 months ago
Modular co-evolution of metabolic networks
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
Jing Zhao, Guohui Ding, Lin Tao, Hong Yu, Zhong-Ha...
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