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138
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BMCBI
2010
87views more  BMCBI 2010»
15 years 4 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
143
Voted
BMCBI
2007
165views more  BMCBI 2007»
15 years 4 months ago
TagSmart: analysis and visualization for yeast mutant fitness data measured by tag microarrays
Background: A nearly complete collection of gene-deletion mutants (96% of annotated open reading frames) of the yeast Saccharomyces cerevisiae has been systematically constructed....
Chulyun Kim, Sangkyum Kim, Russell Dorer, Dan Xie,...
118
Voted
BMCBI
2010
104views more  BMCBI 2010»
15 years 4 months ago
FragViz: visualization of fragmented networks
Background: Researchers in systems biology use network visualization to summarize the results of their analysis. Such networks often include unconnected components, which popular ...
Miha Stajdohar, Minca Mramor, Blaz Zupan, Janez De...
160
Voted
BMCBI
2007
103views more  BMCBI 2007»
15 years 4 months ago
Dynamic simulation of regulatory networks using SQUAD
Background: The ambition of most molecular biologists is the understanding of the intricate network of molecular interactions that control biological systems. As scientists uncove...
Alessandro Di Cara, Abhishek Garg, Giovanni De Mic...
BMCBI
2007
113views more  BMCBI 2007»
15 years 4 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...
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