Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
Background: Many attempts are being made to understand biological subjects at a systems level. A major resource for these approaches are biological databases, storing manifold inf...
Stephan Weise, Ivo Grosse, Christian Klukas, Dirk ...