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110
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BMCBI
2007
132views more  BMCBI 2007»
15 years 3 months ago
Analysis of probe level patterns in Affymetrix microarray data
Background: Microarrays have been used extensively to analyze the expression profiles for thousands of genes in parallel. Most of the widely used methods for analyzing Affymetrix ...
Alexander C. Cambon, Abdelnaby Khalyfa, Nigel G. F...
141
Voted
BMCBI
2007
106views more  BMCBI 2007»
15 years 3 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
139
Voted
BMCBI
2007
152views more  BMCBI 2007»
15 years 3 months ago
Recodon: Coalescent simulation of coding DNA sequences with recombination, migration and demography
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
Miguel Arenas, David Posada
130
Voted
BMCBI
2007
126views more  BMCBI 2007»
15 years 3 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
132
Voted
BMCBI
2007
167views more  BMCBI 2007»
15 years 3 months ago
MindSeer: a portable and extensible tool for visualization of structural and functional neuroimaging data
Background: Three-dimensional (3-D) visualization of multimodality neuroimaging data provides a powerful technique for viewing the relationship between structure and function. A n...
Eider B. Moore, Andrew V. Poliakov, Peter Lincoln,...
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