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BMCBI
2005
98views more  BMCBI 2005»
14 years 9 months ago
The effects of normalization on the correlation structure of microarray data
Background: Stochastic dependence between gene expression levels in microarray data is of critical importance for the methods of statistical inference that resort to pooling test-...
Xing Qiu, Andrew I. Brooks, Lev Klebanov, Andrei Y...
BMCBI
2005
75views more  BMCBI 2005»
14 years 9 months ago
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
Background: The 'lid' subcomplex of the 26S proteasome and the COP9 signalosome (CSN complex) share a common architecture consisting of six subunits harbouring a so-call...
Hartmut Scheel, Kay Hofmann
BMCBI
2005
97views more  BMCBI 2005»
14 years 9 months ago
Modelling the correlation between the activities of adjacent genes in drosophila
Background: Correlation between the expression levels of genes which are located close to each other on the genome has been found in various organisms, including yeast, drosophila...
Helene H. Thygesen, Aeilko H. Zwinderman
BMCBI
2005
159views more  BMCBI 2005»
14 years 9 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...
BMCBI
2005
108views more  BMCBI 2005»
14 years 9 months ago
Storing, linking, and mining microarray databases using SRS
Background: SRS (Sequence Retrieval System) has proven to be a valuable platform for storing, linking, and querying biological databases. Due to the availability of a broad range ...
Antoine Veldhoven, Don de Lange, Marcel Smid, Vict...
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