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» Interactive Protein Manipulation
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BMCBI
2010
107views more  BMCBI 2010»
14 years 4 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy
NAR
2011
222views Computer Vision» more  NAR 2011»
14 years 21 days ago
Effective - a database of predicted secreted bacterial proteins
Protein secretion is a key virulence mechanism of pathogenic and symbiotic bacteria, which makes the investigation of secreted proteins (‘effectors’) crucial for understanding...
Marc-André Jehl, Roland Arnold, Thomas Ratt...
CHI
2001
ACM
15 years 1 months ago
Towards demystification of direct manipulation: cognitive modeling charts the gulf of execution
Direct manipulation involves a large number of interacting psychological mechanisms that make the performance of a given interface hard to predict on intuitive or informal grounds...
David E. Kieras, David Meyer, James A. Ballas
BMCBI
2006
95views more  BMCBI 2006»
14 years 10 months ago
Predicting DNA-binding sites of proteins from amino acid sequence
Background: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach f...
Changhui Yan, Michael Terribilini, Feihong Wu, Rob...