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BMCBI
2005
108views more  BMCBI 2005»
14 years 12 months ago
Storing, linking, and mining microarray databases using SRS
Background: SRS (Sequence Retrieval System) has proven to be a valuable platform for storing, linking, and querying biological databases. Due to the availability of a broad range ...
Antoine Veldhoven, Don de Lange, Marcel Smid, Vict...
JCB
2007
130views more  JCB 2007»
14 years 12 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
BMCBI
2004
150views more  BMCBI 2004»
14 years 12 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
BMCBI
2004
120views more  BMCBI 2004»
14 years 12 months ago
pdb-care (PDB CArbohydrate REsidue check): a program to support annotation of complex carbohydrate structures in PDB files
Background: Carbohydrates are involved in a variety of fundamental biological processes and pathological situations. They therefore have a large pharmaceutical and diagnostic pote...
Thomas Lütteke, Claus-Wilhelm von der Lieth
BMCBI
2004
104views more  BMCBI 2004»
14 years 12 months ago
Discriminative topological features reveal biological network mechanisms
Background: Recent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and soci...
Manuel Middendorf, Etay Ziv, Carter Adams, Jen Hom...