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BMCBI
2010
100views more  BMCBI 2010»
14 years 7 months ago
New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
Background: As protein interactions mediate most cellular mechanisms, protein-protein interaction networks are essential in the study of cellular processes. Consequently, several ...
Laure Sambourg, Nicolas Thierry-Mieg
BMCBI
2010
174views more  BMCBI 2010»
14 years 10 months ago
The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
Junbai Wang
BMCBI
2008
170views more  BMCBI 2008»
14 years 10 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
RECOMB
2005
Springer
15 years 3 months ago
Probabilistic in Silico Prediction of Protein-Peptide Interactions
Abstract. Peptide recognition modules (PRMs) are specialised compact protein domains that mediate many important protein-protein interactions. They are responsible for the assembly...
Wolfgang P. Lehrach, Dirk Husmeier, Christopher K....
JCC
2007
85views more  JCC 2007»
14 years 10 months ago
Quantitative computer simulations of biomolecules: A snapshot
: A recent workshop titled ‘‘Quantitative Computational Biophysics’’ at Florida State University provided an overview of the state of the art in quantitative modeling of bi...
Wei Yang, Hugh Nymeyer, Huan-Xiang Zhou, Bernd A. ...