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BMCBI
2007
173views more  BMCBI 2007»
14 years 9 months ago
Predicting state transitions in the transcriptome and metabolome using a linear dynamical system model
Background: Modelling of time series data should not be an approximation of input data profiles, but rather be able to detect and evaluate dynamical changes in the time series dat...
Ryoko Morioka, Shigehiko Kanaya, Masami Y. Hirai, ...
BMCBI
2008
98views more  BMCBI 2008»
14 years 9 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
BMCBI
2007
197views more  BMCBI 2007»
14 years 9 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
BMCBI
2008
138views more  BMCBI 2008»
14 years 9 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
BMCBI
2008
111views more  BMCBI 2008»
14 years 9 months ago
Molecular docking studies of dithionitrobenzoic acid and its related compounds to protein disulfide isomerase: computational scr
Background: Entry of HIV-1 into human lymphoid requires activities of viral envelope glycoproteins gp120 and gp41, and two host-cell proteins, the primary receptor CD4 and a chemo...
Uthaman Gowthaman, Mannu Jayakanthan, Durai Sundar
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