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BMCBI
2007
102views more  BMCBI 2007»
14 years 12 months ago
Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
Background: The number of algorithms available to predict ligand-protein interactions is large and ever-increasing. The number of test cases used to validate these methods is usua...
Luis A. Diago, Persy Morell, Longendri Aguilera, E...
BMCBI
2007
128views more  BMCBI 2007»
14 years 12 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BMCBI
2007
155views more  BMCBI 2007»
14 years 12 months ago
ProCMD: a database and 3D web resource for protein C mutants
Background: Activated Protein C (ProC) is an anticoagulant plasma serine protease which also plays an important role in controlling inflammation and cell proliferation. Several mu...
Pasqualina D'Ursi, Francesca Marino, Andrea Caprer...
CE
2007
176views more  CE 2007»
14 years 12 months ago
Pedagogical approaches for technology-integrated science teaching
The two separate projects described have examined how teachers exploit computer-based technologies in supporting learning of science at secondary level. This paper examines how pe...
Sara Hennessy, Jocelyn Wishart, Denise Whitelock, ...
COMPLEXITY
2007
116views more  COMPLEXITY 2007»
14 years 12 months ago
Life, information, entropy, and time: Vehicles for semantic inheritance
abstractions provides an additional supra-phenotypic vehicle for semantic inheritance, which supports the cultural heritages around which civilizations revolve. The following three...
Antony R. Crofts