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BMCBI
2007
110views more  BMCBI 2007»
14 years 9 months ago
Analysis of feedback loops and robustness in network evolution based on Boolean models
Background: Many biological networks such as protein-protein interaction networks, signaling networks, and metabolic networks have topological characteristics of a scale-free degr...
Yung-Keun Kwon, Kwang-Hyun Cho
BMCBI
2010
152views more  BMCBI 2010»
14 years 9 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
BMCBI
2007
162views more  BMCBI 2007»
14 years 9 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2008
202views more  BMCBI 2008»
14 years 9 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2007
145views more  BMCBI 2007»
14 years 9 months ago
BioPP: a tool for web-publication of biological networks
Background: Cellular processes depend on the function of intracellular molecular networks. The curation of the literature relevant to specific biological pathways is important for...
Ganesh A. Viswanathan, German Nudelman, Sonali Pat...