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NAR
2011
248views Computer Vision» more  NAR 2011»
14 years 7 months ago
NCBI GEO: archive for functional genomics data sets - 10 years on
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...
CHI
2008
ACM
16 years 4 months ago
Integrating statistics and visualization: case studies of gaining clarity during exploratory data analysis
Although both statistical methods and visualizations have been used by network analysts, exploratory data analysis remains a challenge. We propose that a tight integration of thes...
Adam Perer, Ben Shneiderman
BMCBI
2010
160views more  BMCBI 2010»
15 years 4 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2006
119views more  BMCBI 2006»
15 years 4 months ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
BMCBI
2010
108views more  BMCBI 2010»
14 years 11 months ago
Preferred analysis methods for Affymetrix GeneChips. II. An expanded, balanced, wholly-defined spike-in dataset
Background: Concomitant with the rise in the popularity of DNA microarrays has been a surge of proposed methods for the analysis of microarray data. Fully controlled "spike-i...
Qianqian Zhu, Jeffrey C. Miecznikowski, Marc S. Ha...