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153
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BMCBI
2010
165views more  BMCBI 2010»
15 years 3 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
144
Voted
BMCBI
2010
133views more  BMCBI 2010»
15 years 3 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
150
Voted
BMCBI
2007
127views more  BMCBI 2007»
15 years 3 months ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
152
Voted
CIKM
2005
Springer
15 years 9 months ago
Opportunity map: a visualization framework for fast identification of actionable knowledge
Data mining techniques frequently find a large number of patterns or rules, which make it very difficult for a human analyst to interpret the results and to find the truly interes...
Kaidi Zhao, Bing Liu, Thomas M. Tirpak, Weimin Xia...
PR
2006
116views more  PR 2006»
15 years 3 months ago
Shared farthest neighbor approach to clustering of high dimensionality, low cardinality data
Clustering algorithms are routinely used in biomedical disciplines, and are a basic tool in bioinformatics. Depending on the task at hand, there are two most popular options, the ...
Stefano Rovetta, Francesco Masulli