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BMCBI
2004
117views more  BMCBI 2004»
14 years 9 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
GD
2005
Springer
15 years 3 months ago
D-Dupe: An Interactive Tool for Entity Resolution in Social Networks
Visualizing and analyzing social networks is a challenging problem that has been receiving growing attention. An important first step, before analysis can begin, is ensuring that...
Mustafa Bilgic, Louis Licamele, Lise Getoor, Ben S...
BMCBI
2007
159views more  BMCBI 2007»
14 years 10 months ago
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
Jyoti K. Shah, Harold R. Garner, Michael A. White,...
BMCBI
2011
14 years 1 months ago
Acorn: A grid computing system for constraint based modeling and visualization of the genome scale metabolic reaction networks v
Background: Constraint-based approaches facilitate the prediction of cellular metabolic capabilities, based, in turn on predictions of the repertoire of enzymes encoded in the gen...
Jacek Sroka, Lukasz Bieniasz-Krzywiec, Szymon Gwoz...
BMCBI
2011
14 years 4 months ago
Sequential Interim Analyses of Survival Data in DNA Microarray Experiments
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
Andreas Leha, Tim Beißbarth, Klaus Jung