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BMCBI
2010
106views more  BMCBI 2010»
14 years 10 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
BMCBI
2006
103views more  BMCBI 2006»
14 years 10 months ago
Improving missing value imputation of microarray data by using spot quality weights
Background: Microarray technology has become popular for gene expression profiling, and many analysis tools have been developed for data interpretation. Most of these tools requir...
Peter Johansson, Jari Häkkinen
BMCBI
2004
134views more  BMCBI 2004»
14 years 9 months ago
Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE)
Background: An important challenge for transcript counting methods such as Serial Analysis of Gene Expression (SAGE), "Digital Northern" or Massively Parallel Signature ...
Ricardo Z. N. Vêncio, Helena Brentani, Diogo...
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
OpenDMAP: An open source, ontology-driven concept analysis engine, with applications to capturing knowledge regarding protein tr
Background: Information extraction (IE) efforts are widely acknowledged to be important in harnessing the rapid advance of biomedical knowledge, particularly in areas where import...
Lawrence Hunter, Zhiyong Lu, James Firby, William ...
EVOW
2005
Springer
15 years 3 months ago
Evolutionary Biclustering of Microarray Data
In this work, we address the biclustering of gene expression data with evolutionary computation, which has been proven to have excellent performance on complex problems. In express...
Jesús S. Aguilar-Ruiz, Federico Divina