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118
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MEMICS
2010
14 years 10 months ago
Modeling Gene Networks using Fuzzy Logic
Recently, almost uncontrolled technological progress allows so called high-throughput data collection for sophisticated and complex experimental biological systems analysis. Espec...
Artur Gintrowski
173
Voted
CSB
2005
IEEE
189views Bioinformatics» more  CSB 2005»
15 years 9 months ago
Learning Yeast Gene Functions from Heterogeneous Sources of Data Using Hybrid Weighted Bayesian Networks
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...
Xutao Deng, Huimin Geng, Hesham H. Ali
196
Voted
BMCBI
2005
169views more  BMCBI 2005»
15 years 3 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BIBM
2009
IEEE
155views Bioinformatics» more  BIBM 2009»
15 years 10 months ago
Towards Reliable Isoform Quantification Using RNA-Seq Data
Background: In eukaryotes, alternative splicing often generates multiple splice variants from a single gene. Here weexplore the use of RNA sequencing (RNA-Seq) datasets to address...
Brian E. Howard, Steffen Heber
BMCBI
2006
118views more  BMCBI 2006»
15 years 3 months ago
Gene Expression Profiles Distinguish the Carcinogenic Effects of Aristolochic Acid in Target (Kidney) and Non-target (Liver) Tis
Background: Aristolochic acid (AA) is the active component of herbal drugs derived from Aristolochia species that have been used for medicinal purposes since antiquity. AA, howeve...
Tao Chen, Lei Guo, Lu Zhang 0013, Leming M. Shi, H...