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BMCBI
2008
159views more  BMCBI 2008»
14 years 12 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2006
166views more  BMCBI 2006»
14 years 12 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
BMCBI
2007
168views more  BMCBI 2007»
14 years 11 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
BMCBI
2004
150views more  BMCBI 2004»
14 years 11 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty
CN
2000
98views more  CN 2000»
14 years 11 months ago
Dynamic pricing by software agents
We envision a future in which the global economy and the Internet will merge and evolve together into an information economy bustling with billions of economically motivated softw...
Jeffrey O. Kephart, James E. Hanson, Amy R. Greenw...