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» Interactive visual analysis of time-series microarray data
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BMCBI
2010
214views more  BMCBI 2010»
14 years 9 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BIOINFORMATICS
2002
146views more  BIOINFORMATICS 2002»
14 years 9 months ago
A duplication growth model of gene expression networks
Motivation: There has been considerable interest in developing computational techniques for inferring genetic regulatory networks from whole-genome expression profiles. When expre...
Ashish Bhan, David J. Galas, T. Gregory Dewey
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BMCBI
2005
148views more  BMCBI 2005»
14 years 9 months ago
Nonparametric tests for differential gene expression and interaction effects in multi-factorial microarray experiments
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
Xin Gao, Peter X. K. Song
TMI
2010
165views more  TMI 2010»
14 years 8 months ago
Spatio-Temporal Data Fusion for 3D+T Image Reconstruction in Cerebral Angiography
—This paper provides a framework for generating high resolution time sequences of 3D images that show the dynamics of cerebral blood flow. These sequences have the potential to ...
Andrew Copeland, Rami Mangoubi, Mukund N. Desai, S...