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BMCBI
2008
106views more  BMCBI 2008»
15 years 3 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...
BMCBI
2010
113views more  BMCBI 2010»
15 years 3 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
BMCBI
2008
153views more  BMCBI 2008»
15 years 3 months ago
2DB: a Proteomics database for storage, analysis, presentation, and retrieval of information from mass spectrometric experiments
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational anal...
Jens Allmer, Sebastian Kuhlgert, Michael Hippler
BMCBI
2008
118views more  BMCBI 2008»
15 years 3 months ago
DOVIS: an implementation for high-throughput virtual screening using AutoDock
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
Shuxing Zhang, Kamal Kumar, Xiaohui Jiang, Anders ...
BMCBI
2007
154views more  BMCBI 2007»
15 years 3 months ago
PepBank - a database of peptides based on sequence text mining and public peptide data sources
Background: Peptides are important molecules with diverse biological functions and biomedical uses. To date, there does not exist a single, searchable archive for peptide sequence...
Timur Shtatland, Daniel Guettler, Misha Kossodo, M...
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