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» Internal loops in RNA secondary structure prediction
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EVOW
2004
Springer
15 years 3 months ago
Two-Step Genetic Programming for Optimization of RNA Common-Structure
We present an algorithm for identifying putative non-coding RNA (ncRNA) using an RCSG (RNA Common-Structural Grammar) and show the effectiveness of the algorithm. The algorithm con...
Jin-Wu Nam, Je-Gun Joung, Y. S. Ahn, Byoung-Tak Zh...
BMCBI
2004
151views more  BMCBI 2004»
14 years 9 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BMCBI
2006
82views more  BMCBI 2006»
14 years 9 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
ISMB
2004
14 years 11 months ago
Exploiting conserved structure for faster annotation of non-coding RNAs without loss of accuracy
Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
Zasha Weinberg, Walter L. Ruzzo
WABI
2007
Springer
133views Bioinformatics» more  WABI 2007»
15 years 3 months ago
RNA Folding Including Pseudoknots: A New Parameterized Algorithm and Improved Upper Bound
Predicting the secondary structure of an RNA sequence is an important problem in structural bioinformatics. The general RNA folding problem, where the sequence to be folded may con...
Chunmei Liu, Yinglei Song, Louis W. Shapiro