Background: Secondary structure is used in hierarchical classification of protein structures, identification of protein features, such as helix caps and loops, for fold recognitio...
Maria Vittoria Cubellis, Fabien Cailliez, Simon C....
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Programs for RNA mutational analysis that are structure-based and rely on secondary structure prediction have been developed and expanded in the past several years. They can be us...
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
Background: One of the strategies for protein function annotation is to search particular structural motifs that are known to be shared by proteins with a given function. Results:...