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» Internal loops in RNA secondary structure prediction
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BMCBI
2006
158views more  BMCBI 2006»
14 years 9 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
IPPS
2008
IEEE
15 years 4 months ago
On the Effectiveness of Rebuilding RNA Secondary Structures from Sequence Chunks
Despite the computing power of emerging technologies, predicting long RNA secondary structures with thermodynamics-based methods is still infeasible, especially if the structures ...
Michela Taufer, Thamar Solorio, Abel Licon, David ...
BIOCOMP
2009
14 years 10 months ago
Consensus RNA Secondary Structure Prediction by Ranking k-Length Stems
The accurate computational prediction of RNA secondary structures is a difficult task, but an important one, since RNA structure is usually more evolutionarily conserved than prima...
Denise Y. F. Mak, Gary Benson
BIBE
2007
IEEE
138views Bioinformatics» more  BIBE 2007»
15 years 4 months ago
A Flexible Stem-Based Local Search Algorithm for Predicting RNA Secondary Structures Including Pseudoknots
-We demonstrate a new algorithm named FlexStem to predict RNA secondary structures with pseudoknots. Our approach is based on the free energy minimization criterion, and utilizes a...
Xiang Chen, Simin He, Dongbo Bu, Runsheng Chen, We...
ICDM
2007
IEEE
131views Data Mining» more  ICDM 2007»
15 years 4 months ago
Characterizing RNA Secondary-Structure Features and Their Effects on Splice-Site Prediction
— RNA molecules are distinguished by their sequence composition and by their three-dimensional shape, called the secondary structure. The secondary structure of a pre-mRNA sequen...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur