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BMCBI
2007
180views more  BMCBI 2007»
14 years 9 months ago
Splicy: a web-based tool for the prediction of possible alternative splicing events from Affymetrix probeset data
Background: The Affymetrix™ technology is nowadays a well-established method for the analysis of gene expression profiles in cancer research studies. However, changes in gene ex...
Davide Rambaldi, Barbara Felice, Viviane Praz, Phi...
BMCBI
2007
120views more  BMCBI 2007»
14 years 9 months ago
Transcript-based redefinition of grouped oligonucleotide probe sets using AceView: High-resolution annotation for microarrays
Background: Extracting biological information from high-density Affymetrix arrays is a multi-step process that begins with the accurate annotation of microarray probes. Shortfalls...
Jun Lu, Joseph C. Lee, Marc L. Salit, Margaret C. ...
BMCBI
2010
92views more  BMCBI 2010»
14 years 9 months ago
Integrating gene expression and GO classification for PCA by preclustering
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
Jorn R. de Haan, Ester Piek, René C. van Sc...
BMCBI
2004
100views more  BMCBI 2004»
14 years 9 months ago
Handling multiple testing while interpreting microarrays with the Gene Ontology Database
Background: The development of software tools that analyze microarray data in the context of genetic knowledgebases is being pursued by multiple research groups using different me...
Michael V. Osier, Hongyu Zhao, Kei-Hoi Cheung
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JIB
2006
110views more  JIB 2006»
14 years 9 months ago
Combining biomedical knowledge and transcriptomic data to extract new knowledge on genes
In biomedical research, interpretation of microarray data requires confrontation of data and knowledge from heterogeneous resources, either in the biomedical domain or in genomics...
Emilie Guérin, Gwenaëlle Marquet, Juli...