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BIOINFORMATICS
2007
137views more  BIOINFORMATICS 2007»
14 years 9 months ago
Annotation-based distance measures for patient subgroup discovery in clinical microarray studies
: Background Clustering algorithms are widely used in the analysis of microarray data. In clinical studies, they are often applied to find groups of co-regulated genes. Clustering...
Claudio Lottaz, Joern Toedling, Rainer Spang
BMCBI
2005
113views more  BMCBI 2005»
14 years 9 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
MICCAI
2004
Springer
15 years 10 months ago
Landmark-Driven, Atlas-Based Segmentation of Mouse Brain Tissue Images Containing Gene Expression Data
To better understand the development and function of the mammalian brain, researchers have begun to systematically collect a large number of gene expression patterns throughout the...
Ioannis A. Kakadiaris, Musodiq Bello, Shiva Arunac...
BMCBI
2008
106views more  BMCBI 2008»
14 years 9 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BIBE
2004
IEEE
107views Bioinformatics» more  BIBE 2004»
15 years 1 months ago
Enhanced pClustering and Its Applications to Gene Expression Data
Clustering has been one of the most popular methods to discover useful biological insights from DNA microarray. An interesting paradigm is simultaneous clustering of both genes an...
Sungroh Yoon, Christine Nardini, Luca Benini, Giov...