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BMCBI
2010
214views more  BMCBI 2010»
14 years 9 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
107views more  BMCBI 2010»
14 years 9 months ago
Semantic annotation of morphological descriptions: an overall strategy
Background: Large volumes of morphological descriptions of whole organisms have been created as print or electronic text in a human-readable format. Converting the descriptions in...
Hong Cui
BMCBI
2010
122views more  BMCBI 2010»
14 years 9 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
BMCBI
2010
111views more  BMCBI 2010»
14 years 9 months ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
BMCBI
2010
125views more  BMCBI 2010»
14 years 9 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
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