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BMCBI
2010
161views more  BMCBI 2010»
14 years 12 months ago
CGHpower: exploring sample size calculations for chromosomal copy number experiments
Background: Determining a suitable sample size is an important step in the planning of microarray experiments. Increasing the number of arrays gives more statistical power, but ad...
Ilari Scheinin, Jose A. Ferreira, Sakari Knuutila,...
BMCBI
2010
136views more  BMCBI 2010»
14 years 12 months ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
BMCBI
2010
134views more  BMCBI 2010»
14 years 12 months ago
ScreenMill: A freely available software suite for growth measurement, analysis and visualization of high-throughput screen data
Background: Many high-throughput genomic experiments, such as Synthetic Genetic Array and yeast two-hybrid, use colony growth on solid media as a screen metric. These experiments ...
John C. Dittmar, Robert J. D. Reid, Rodney Rothste...
BMCBI
2010
109views more  BMCBI 2010»
14 years 12 months ago
ParallABEL: an R library for generalized parallelization of genome-wide association studies
Background: Genome-Wide Association (GWA) analysis is a powerful method for identifying loci associated with complex traits and drug response. Parts of GWA analyses, especially th...
Unitsa Sangket, Surakameth Mahasirimongkol, Wasun ...
BMCBI
2010
109views more  BMCBI 2010»
14 years 12 months ago
Pripper: prediction of caspase cleavage sites from whole proteomes
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
Mirva Piippo, Niina Lietzén, Olli Nevalaine...
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