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BMCBI
2008
121views more  BMCBI 2008»
15 years 6 months ago
Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
BMCBI
2008
124views more  BMCBI 2008»
15 years 6 months ago
RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
Background: Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technolog...
Romesh Stanislaus, Mark Carey, Helena F. Deus, Kev...
BMCBI
2008
141views more  BMCBI 2008»
15 years 6 months ago
Ontology-guided data preparation for discovering genotype-phenotype relationships
Complexity of post-genomic data and multiplicity of mining strategies are two limits to Knowledge Discovery in Databases (KDD) in life sciences. Because they provide a semantic fr...
Adrien Coulet, Malika Smaïl-Tabbone, Pascale ...
BMCBI
2008
127views more  BMCBI 2008»
15 years 6 months ago
AMMO-Prot: amine system project 3D-model finder
Background: Amines are biogenic amino acid derivatives, which play pleiotropic and very important yet complex roles in animal physiology. For many other relevant biomolecules, bio...
Ismael Navas Delgado, Raúl Montañez,...
BMCBI
2008
85views more  BMCBI 2008»
15 years 6 months ago
Wanted: unique names for unique atom positions. PDB-wide analysis of diastereotopic atom names of small molecules containing dip
Background: Biological chemistry is very stereospecific. Nonetheless, the diastereotopic oxygen atoms of diphosphate-containing molecules in the Protein Data Bank (PDB) are often ...
Christopher A. Bottoms, Dong Xu
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