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» Is Structural Subtyping Useful
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BMCBI
2007
160views more  BMCBI 2007»
15 years 4 months ago
Convergent algorithms for protein structural alignment
Background: Many algorithms exist for protein structural alignment, based on internal protein coordinates or on explicit superposition of the structures. These methods are usually...
Leandro Martínez, Roberto Andreani, Jos&eac...
135
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BMCBI
2007
183views more  BMCBI 2007»
15 years 4 months ago
Considerations in the identification of functional RNA structural elements in genomic alignments
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
Tomas Babak, Benjamin J. Blencowe, Timothy R. Hugh...
125
Voted
BMCBI
2006
158views more  BMCBI 2006»
15 years 4 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...
144
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BMCBI
2005
77views more  BMCBI 2005»
15 years 4 months ago
Structural comparison of metabolic networks in selected single cell organisms
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
Dongxiao Zhu, Zhaohui S. Qin
131
Voted
ALGORITHMICA
2004
132views more  ALGORITHMICA 2004»
15 years 4 months ago
A General Model for Authenticated Data Structures
Query answers from on-line databases can easily be corrupted by hackers or malicious database publishers. Thus it is important to provide mechanisms which allow clients to trust th...
Charles U. Martel, Glen Nuckolls, Premkumar T. Dev...