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123
Voted
BMCBI
2010
2010
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
15 years 3 months ago
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
107
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: An explosive global spreading of multidrug resistant Mycobacterium tuberculosis (Mtb) is a catastrophe, which demands an urgent need to design or develop novel/potent ...
141
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
129
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: The pyridine nucleotide disulfide reductase (PNDR) is a large and heterogeneous protein family divided into two classes (I and II), which reflect the divergent evoluti...
111
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Peptidases are proteolytic enzymes responsible for fundamental cellular activities in all organisms. Apparently about 2–5% of the genes encode for peptidases, irresp...