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BMCBI
2007
121views more  BMCBI 2007»
14 years 12 months ago
Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines
Background: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epito...
Huynh-Hoa Bui, John Sidney, Wei Li, Nicholas Fusse...
BMCBI
2007
100views more  BMCBI 2007»
14 years 12 months ago
PARE: A tool for comparing protein abundance and mRNA expression data
Background: Techniques for measuring protein abundance are rapidly advancing and we are now in a situation where we anticipate many protein abundance data sets will be available i...
Eric Z. Yu, Anne E. Counterman Burba, Mark Gerstei...
BMCBI
2008
200views more  BMCBI 2008»
14 years 12 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2007
146views more  BMCBI 2007»
14 years 12 months ago
Spatial location and its relevance for terminological inferences in bio-ontologies
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
Stefan Schulz, Kornél G. Markó, Udo ...
BMCBI
2008
132views more  BMCBI 2008»
14 years 12 months ago
Exon level integration of proteomics and microarray data
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in par...
Danny A. Bitton, Michal J. Okoniewski, Yvonne Conn...