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BMCBI
2008
135views more  BMCBI 2008»
15 years 12 hour ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2008
130views more  BMCBI 2008»
15 years 12 hour ago
IDEA: Interactive Display for Evolutionary Analyses
Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...
Amy Egan, Anup Mahurkar, Jonathan Crabtree, Jonath...
BMCBI
2007
89views more  BMCBI 2007»
15 years 12 hour ago
Primique: automatic design of specific PCR primers for each sequence in a family
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...
Jakob Fredslund, Mette Lange
BMCBI
2008
118views more  BMCBI 2008»
15 years 11 hour ago
DOVIS: an implementation for high-throughput virtual screening using AutoDock
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
Shuxing Zhang, Kamal Kumar, Xiaohui Jiang, Anders ...
BMCBI
2008
123views more  BMCBI 2008»
15 years 11 hour ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
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