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WSC
1998
15 years 3 months ago
Informational Macrodynamics: System Modelling and Simulation Methodologies
Informational Macrodynamics (IMD) presents a unified informational systemic approach with common information language for modeling, analysis and optimization of a variety of inter...
Vladimir S. Lerner
85
Voted
APBC
2004
15 years 3 months ago
Representing Experimental Biological Data in Metabolic Networks
This paper describes a novel approach to representing experimental biological data in metabolic networks. The aim is to allow biologists to visualise and analyse the data in the c...
Tim Dwyer, Hardy Rolletschek, Falk Schreiber
85
Voted
RECOMB
2008
Springer
16 years 2 months ago
Bootstrapping the Interactome: Unsupervised Identification of Protein Complexes in Yeast
Protein interactions and complexes are major components of biological systems. Recent genome-wide applications of tandem affinity purification (TAP) in yeast have increased signifi...
Caroline C. Friedel, Jan Krumsiek, Ralf Zimmer
124
Voted
BMCBI
2007
104views more  BMCBI 2007»
15 years 1 months ago
A response to Yu et al. "A forward-backward fragment assembling algorithm for the identification of genomic amplification and de
Background: Yu et al. (BMC Bioinformatics 2007,8: 145+) have recently compared the performance of several methods for the detection of genomic amplification and deletion breakpoin...
Oscar M. Rueda, Ramón Díaz-Uriarte
144
Voted
BMCBI
2006
194views more  BMCBI 2006»
15 years 1 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...