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100
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TCBB
2010
89views more  TCBB 2010»
15 years 7 days ago
Model Composition for Macromolecular Regulatory Networks
—Models of regulatory networks become more difficult to construct and understand as they grow in size and complexity. Large models are usually built up from smaller models, repre...
Ranjit Randhawa, Clifford A. Shaffer, John J. Tyso...
114
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BMCBI
2007
126views more  BMCBI 2007»
15 years 2 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
142
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BMCBI
2007
136views more  BMCBI 2007»
15 years 1 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
126
Voted
BMCBI
2008
142views more  BMCBI 2008»
15 years 2 months ago
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
Irene Kouskoumvekaki, Zhiyong Yang, Svava Ó...
BMCBI
2011
14 years 9 months ago
NClassG+: A classifier for non-classically secreted Gram-positive bacterial proteins
Background: Most predictive methods currently available for the identification of protein secretion mechanisms have focused on classically secreted proteins. In fact, only two met...
Daniel Restrepo-Montoya, Camilo Pino, Luis F. Ni&n...