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BMCBI
2006
110views more  BMCBI 2006»
15 years 2 months ago
Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...
PSB
2003
15 years 3 months ago
Decomposing Gene Expression into Cellular Processes
We propose a probabilistic model for cellular processes, and an algorithm for discovering them from gene expression data. A process is associated with a set of genes that particip...
Eran Segal, Alexis Battle, Daphne Koller
TACAS
2007
Springer
99views Algorithms» more  TACAS 2007»
15 years 8 months ago
"Don't Care" Modeling: A Logical Framework for Developing Predictive System Models
Analysis of biological data often requires an understanding of components of pathways and/or networks and their mutual dependency relationships. Such systems are often analyzed and...
Hillel Kugler, Amir Pnueli, Michael J. Stern, E. J...
BMCBI
2007
121views more  BMCBI 2007»
15 years 2 months ago
Predicting zinc binding at the proteome level
Background: Metalloproteins are proteins capable of binding one or more metal ions, which may be required for their biological function, for regulation of their activities or for ...
Andrea Passerini, Claudia Andreini, Sauro Menchett...
CMSB
2011
Springer
14 years 1 months ago
The singular power of the environment on stochastic nonlinear threshold Boolean automata networks
Abstract. This paper tackles theoretically the question of the structural stability of biological regulation networks subjected to the influence of their environment. The model of...
Jacques Demongeot, Sylvain Sené