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BMCBI
2010
122views more  BMCBI 2010»
15 years 1 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
BMCBI
2008
130views more  BMCBI 2008»
15 years 1 months ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
BMCBI
2010
167views more  BMCBI 2010»
15 years 1 months ago
Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of met
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
Melissa J. Morine, Jolene McMonagle, Sinead Toomey...
BMCBI
2011
14 years 8 months ago
Phenotype Recognition with Combined Features and Random Subspace Classifier Ensemble
Background: Automated, image based high-content screening is a fundamental tool for discovery in biological science. Modern robotic fluorescence microscopes are able to capture th...
Bailing Zhang, Tuan D. Pham
CIKM
2010
Springer
14 years 11 months ago
Regularization and feature selection for networked features
In the standard formalization of supervised learning problems, a datum is represented as a vector of features without prior knowledge about relationships among features. However, ...
Hongliang Fei, Brian Quanz, Jun Huan