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BMCBI
2010
89views more  BMCBI 2010»
14 years 10 months ago
Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS)
Background: Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentratio...
Jennifer M. Staab, Thomas M. O'Connell, Shawn M. G...
BMCBI
2010
136views more  BMCBI 2010»
14 years 10 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2008
178views more  BMCBI 2008»
14 years 10 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2008
108views more  BMCBI 2008»
14 years 10 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
LREC
2010
160views Education» more  LREC 2010»
14 years 11 months ago
Construction of Back-Channel Utterance Corpus for Responsive Spoken Dialogue System Development
In spoken dialogues, if a spoken dialogue system does not respond at all during user's utterances, the user might feel uneasy because the user does not know whether or not th...
Yuki Kamiya, Tomohiro Ohno, Shigeki Matsubara, Hid...