Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
Background: In the microarray experiment, many undesirable systematic variations are commonly observed. Normalization is the process of removing such variation that affects the me...
Dankyu Yoon, Sung-Gon Yi, Ju-Han Kim, Taesung Park
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...