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BMCBI
2007
226views more  BMCBI 2007»
14 years 10 months ago
MiRFinder: an improved approach and software implementation for genome-wide fast microRNA precursor scans
Background: MicroRNAs (miRNAs) are recognized as one of the most important families of noncoding RNAs that serve as important sequence-specific post-transcriptional regulators of ...
Ting-Hua Huang, Bin Fan, Max F. Rothschild, Zhi-Li...
ICCS
2009
Springer
15 years 4 months ago
GPU Accelerated RNA Folding Algorithm
Many bioinformatics studies require the analysis of RNA or DNA structures. More specifically, extensive work is done to elaborate efficient algorithms able to predict the 2-D fold...
Guillaume Rizk, Dominique Lavenier
RECOMB
2006
Springer
15 years 10 months ago
A Study of Accessible Motifs and RNA Folding Complexity
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...
DNA
2009
Springer
185views Bioinformatics» more  DNA 2009»
15 years 4 months ago
NP-Completeness of the Direct Energy Barrier Problem without Pseudoknots
Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in desig...
Ján Manuch, Chris Thachuk, Ladislav Stacho,...
JCB
2007
108views more  JCB 2007»
14 years 9 months ago
A Dynamic Programming Approach for Finding Common Patterns in RNAs
We developed a dynamic programming approach of computing common sequence structure patterns among two RNAs given their primary sequences and their secondary structures. Common pat...
Sven Siebert, Rolf Backofen